This 5-page activity guide from 3D Molecular Designs shows students how PCR (polymerase chain reaction) works using a hands-on model. Students are guided through each step of the process, including heating DNA to separate it (denaturation), adding primers (annealing), and building new DNA strands (extension). The repetition of PCR is emphasized, where the three stages are repeated 20-40 times, doubling the number of DNA copies with each cycle. 

Diagrams of each cycle, notes, and resources used are included.

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